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ATC R07AX30 · Other Respiratory System Products
Ivacaftor and Lumacaftor shortage
As of 31 Oct 2026, Ivacaftor and Lumacaftor has a reported shortage in 2 of the 5 countries we track (Italy, Spain), covering 2 products.
Countries2/5
Products2packs or presentations
Short since27 Aug 202514 months ago
Earliest returnnot givencompany estimate
No return date2products
Main reasonManufacturing problem
Timeline
ItalySpain
Solid bars run from the reported start to today; faded bars show the time left until the expected return. An arrow means no return date was given.
Affected products
| Country | Product | Holder | Since | Expected back | Reason |
|---|---|---|---|---|---|
| IT | ORKAMBI | VERTEX PHARMACEUTICALS (IRELAND) LIMITED | 6 Oct 2026 | not given | Manufacturing problem Problemi produttivi |
| ES | ORKAMBI 75 MG/94 MG GRANULADO EN SOBRE, 56 sobres | Vertex Pharmaceuticals (Ireland) Limited | 27 Aug 2025 | not given | Not stated |
"Expected back" is the date the company gave the authority, when it gave one. Ask a pharmacist about alternatives.