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ATC G03CA03 · Sex Hormones and Modulators of the Genital System

Estradiol shortage

As of 31 Oct 2026, Estradiol has a reported shortage in 3 of the 5 countries we track (Italy, Spain, Belgium), covering 14 products.

Countries3/5
Products14packs or presentations
Short since15 Mar 20268 months ago
Earliest return4 Nov 2026company estimate
No return date3products
Main reasonNot stated
GermanyNo reported shortageItaly3 packs shortSpain6 packs shortAustriaNo reported shortageBelgium5 packs short

Timeline

ItalySpainBelgium
2027LENZETTOLENZETTOESTREVAESTREVALENZETTO 1,53 MG/DOSIS SOLUCION PARA PULVERILENZETTO 1,53 MG/DOSIS SOLUCION PARA PULVERIZACION TRANSDERMICA, 1 frasco de 6,5 ml (56 pulverizaciones)EVOPAD 25 microgramos/24 H PARCHES TRANSDERMEVOPAD 25 microgramos/24 H PARCHES TRANSDERMICOS, 8 parchesEVOPAD 50 microgramos/24 H PARCHES TRANSDERMEVOPAD 50 microgramos/24 H PARCHES TRANSDERMICOS, 8 parchesEVOPAD 75 microgramos/24 H PARCHES TRANSDERMEVOPAD 75 microgramos/24 H PARCHES TRANSDERMICOS, 8 parchesESTRADOT 50 microgramos/24 HORAS, PARCHE TRAESTRADOT 50 microgramos/24 HORAS, PARCHE TRANSDERMICO , 8 parchesESTRADOT 25 microgramos/24 HORAS, PARCHE TRAESTRADOT 25 microgramos/24 HORAS, PARCHE TRANSDERMICO , 8 parchesDermestril 25 µg transderm. patch 26 (2 mg)Dermestril 25 µg transderm. patch 26 (2 mg)Systen 50 µg/24 h transderm. patch 24Systen 50 µg/24 h transderm. patch 24Feminova 50 50 µg/24 h transderm. patch 12Feminova 50 50 µg/24 h transderm. patch 12Lenzetto 1.53 mg/dose transderm. spray sol. Lenzetto 1.53 mg/dose transderm. spray sol. met. pump 6.5 ml (56 doses)Rewellfem 10 µg vagin. tabl. 18Rewellfem 10 µg vagin. tabl. 18today

Solid bars run from the reported start to today; faded bars show the time left until the expected return. An arrow means no return date was given.

Affected products

CountryProductHolderSinceExpected backReason
ITLENZETTOGEDEON RICHTER PLC1 Sep 202631 Mar 2027Increased demand
Elevata richiesta/problemi produttivi
ITESTREVATHERAMEX IRELAND LIMITED31 Oct 202615 Jan 2027Increased demand
Elevata richiesta/problemi produttivi (carenza relativa solo al canale retail)
ITESTRADERM MX announcedMerus Labs Luxco II S.à.r.l.1 Dec 202631 Mar 2027Increased demand
Elevata richiesta
ESLENZETTO 1,53 MG/DOSIS SOLUCION PARA PULVERIZACION TRANSDERMICA, 1 frasco de 6,5 ml (56 pulverizaciones)Gedeon Richter Plc.15 Mar 202629 Nov 2026Not stated
ESEVOPAD 25 microgramos/24 H PARCHES TRANSDERMICOS, 8 parchesTheramex Ireland Limited3 Sep 20264 Nov 2026Not stated
ESEVOPAD 50 microgramos/24 H PARCHES TRANSDERMICOS, 8 parchesTheramex Ireland Limited6 Oct 20264 Nov 2026Not stated
ESEVOPAD 75 microgramos/24 H PARCHES TRANSDERMICOS, 8 parchesTheramex Ireland Limited18 Oct 2026not givenNot stated
ESESTRADOT 50 microgramos/24 HORAS, PARCHE TRANSDERMICO , 8 parchesBexal Farmaceutica S.A.19 Oct 2026not givenNot stated
ESESTRADOT 25 microgramos/24 HORAS, PARCHE TRANSDERMICO , 8 parchesBexal Farmaceutica S.A.20 Oct 2026not givenNot stated
BEDermestril 25 µg transderm. patch 26 (2 mg)Besins Healthcare4 Jun 202630 Nov 2026Manufacturing problem
Delay in the release of the end product
BESysten 50 µg/24 h transderm. patch 24Theramex Ireland31 Jul 202616 Dec 2026Increased demand
BEFeminova 50 50 µg/24 h transderm. patch 12Theramex Ireland6 Oct 202614 Jan 2027Increased demand
BELenzetto 1.53 mg/dose transderm. spray sol. met. pump 6.5 ml (56 doses)Gedeon Richter7 Oct 20266 Nov 2026Distribution or logistics
Logistic problems (transport, customs, ...)
BERewellfem 10 µg vagin. tabl. 18Gedeon Richter21 Oct 202612 Nov 2026Other
Other reason

"Expected back" is the date the company gave the authority, when it gave one. Ask a pharmacist about alternatives.

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