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ATC A16AB22 · Other Alimentary Tract and Metabolism Products

Avalglucosidase Alfa shortage

As of 31 Oct 2026, Avalglucosidase Alfa has a reported shortage in 5 of the 5 countries we track (Germany, Italy, Spain, Austria, Belgium), covering 9 products.

Countries5/5
Products9packs or presentations
Short since18 Mar 202519 months ago
Earliest return6 Nov 2026company estimate
No return date2products
Main reasonManufacturing problem
Germany3 packs shortItaly1 pack shortSpain1 pack shortAustria1 pack shortBelgium3 packs short

Timeline

GermanyItalySpainAustriaBelgium
202620272028NexviadymeNexviadymeNexviadymeNexviadymeNexviadymeNexviadymeNEXVIADYMENEXVIADYMENEXVIADYME 100 MG POLVO PARA CONCENTRADO PARNEXVIADYME 100 MG POLVO PARA CONCENTRADO PARA SOLUCION PARA PERFUSION, 1 vialNexviadyme 100 mg Pulver für ein Konzentrat Nexviadyme 100 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung, 10 StückNexviadyme 100 mg inj. sol. (pwdr., conc.) iNexviadyme 100 mg inj. sol. (pwdr., conc.) i.v. vial 10 x 100 mgNexviadyme 100 mg inj. sol. (pwdr., conc.) iNexviadyme 100 mg inj. sol. (pwdr., conc.) i.v. vial 5 x 100 mgNexviadyme 100 mg inj. sol. (pwdr., conc.) iNexviadyme 100 mg inj. sol. (pwdr., conc.) i.v. vial 100 mgtoday

Solid bars run from the reported start to today; faded bars show the time left until the expected return. An arrow means no return date was given.

Affected products

CountryProductHolderSinceExpected backReason
DENexviadymeSanofi B.V.3 Jul 202631 Dec 2026Manufacturing problem
Probleme bei der Endfreigabe
DENexviadymeSanofi B.V.3 Jul 202631 Dec 2026Manufacturing problem
Probleme bei der Endfreigabe
DENexviadymeSanofi B.V.3 Jul 202631 Dec 2026Manufacturing problem
Probleme bei der Endfreigabe
ITNEXVIADYMESANOFI B.V.23 Jun 2026not givenManufacturing problem
Problemi produttivi
ESNEXVIADYME 100 MG POLVO PARA CONCENTRADO PARA SOLUCION PARA PERFUSION, 1 vialSanofi B.V.2 Jul 202619 Nov 2026Not stated
ATNexviadyme 100 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung, 10 StückSanofi B.V.18 Mar 2025not givenManufacturing problem
Kapazitätsengpässe bei der Herstellung
BENexviadyme 100 mg inj. sol. (pwdr., conc.) i.v. vial 10 x 100 mgSanofi24 Mar 202531 Dec 2027Other
Other reason
BENexviadyme 100 mg inj. sol. (pwdr., conc.) i.v. vial 5 x 100 mgSanofi9 Apr 202531 Dec 2027Other
Other reason
BENexviadyme 100 mg inj. sol. (pwdr., conc.) i.v. vial 100 mgSanofi31 Aug 20266 Nov 2026Manufacturing problem
Delay in the release of the end product

"Expected back" is the date the company gave the authority, when it gave one. Ask a pharmacist about alternatives.

Related medicines also in short supply

Alglucosidase Alfa Olipudase Alfa Velmanase Alfa